Metabolomics 

(noun. /me-ta-buh-LO-miks/)

by Yasemin Cole

What does it mean? 

The study of all the global small molecules (also called metabolites) within a living organism, biosample/specimen, tissue, or cells. “Small” molecules typically have a mass between  50 – 1500 grams per mole (grams per mole is also called “daltons”, abbreviated Da). 

How do I use it in a sentence?

“Rather than analyzing a handful of known chemicals at a time, the researcher decided to use metabolomics to analyze hundreds to thousands of metabolites.”

Metabolomics Workflow – starting from the source material (e.g., mouse, bacteria) to extraction of metabolites to running the sample on the mass spectrometry machine. (Image created & modified by the author on BioRender).

Etymology

English: The term was coined in the late 1990s by combining the words metabolome + -ics.Similar to the creation of the word “genomics,” indicating the study of the complete genome, metabolomics would encompass the global picture of metabolites.

Examples of “omics” fields: 

Genomics = study of whole set of genes
Metabolomics = study of whole set of metabolites (small molecules)
Proteomics = study of whole set of proteins 

Fields of study in which this word is commonly used

Genomics
Precision medicine
Omic technologies